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Chicago Native Pope Leo Has Lung Cancer, Undergoes Successful Surgery

Doctors removed the lower lobe of the pontiff's right lung Tuesday, the Vatican said.

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Medical Director Andrea Cambieri, right, greets Pope Leo XIV as he arrives at the Agostino Gemelli Polyclinic in Rome on Tuesday, where doctors operated to remove a lung nodule. (AP Photo/Gregorio Borgia)

CHICAGO — Pope Leo XIV, the Chicago-area native who became the first American pope last year, underwent successful surgery Tuesday in Rome that confirmed a lung cancer diagnosis, according to the Vatican.

Doctors removed the lower lobe of his right lung at Gemelli Hospital using a video-assisted technique. Testing of tissue during the procedure confirmed lung adenocarcinoma, a diagnosis suspected before the operation, Vatican News reported.

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The surgery lasted about 90 minutes, with Leo spending approximately three hours in the operating room. Doctors reported no complications. He awoke normally and returned to his room on the hospital's 10th floor after a brief observation period, the Vatican said.

The medical update came in a statement from Dr. Luigi Carbone and Professor Stefano Margaritora released by the Holy See Press Office. Margaritora led the surgical team.

RELATED: Chicago Native Becomes 1st American Pope

Vatican spokesman Matteo Bruni said Monday that the nodule had been discovered during routine medical examinations. Leo is expected to remain hospitalized for about a week following surgery.

Before entering the hospital Tuesday, the pope greeted hospital leaders and several patients, including people in wheelchairs, as well-wishers gathered outside.

Born Robert Prevost, Leo grew up in south suburban Dolton and was elected May 8, 2025, succeeding Pope Francis. A member of the Augustinian religious order, he spent years ministering in Peru before Francis brought him to the Vatican in 2023 to oversee the office that reviews bishop nominations worldwide.

His Chicago roots have remained a recurring connection for local residents. In August, U.S. Rep. Raja Krishnamoorthi presented the noted White Sox fan with a custom Cubs jersey reading "Da Pope," with No. 267 recognizing his place as the church's 267th pontiff.

Patch also covered Leo's public disagreements with President Donald Trump in April over the war in Iran, including the pope's criticism of Trump's threat against Iranian civilization and his subsequent response to the president's attacks.

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