Business & Tech

AB SCIEX and Illumina Collaborate to Create World's First Multi-omics Cloud-Computing Environment

AB SCIEX, headquartered in Framingham, enables scientists and laboratory analysts to find answers to the complex analytical challenges.

AB SCIEX and Illumina announced the OneOmics™ project, an exclusive partnership to bring together SWATH™-based next-generation proteomics and next-generation sequencing tools in a cloud computing environment.

The AB SCIEX SWATH™ Proteomics Cloud Tool Kit suite of applications will be hosted in BaseSpace, Illumina’s applications store and cloud-based informatics community dedicated to advancing genomic analysis. This partnership enables BaseSpace as a single location for genomics and proteomics “big data.” With fast, secure, and streamlined analysis of complex multi-omics data sets, this solution will help advance biomarker discovery and aid research into diseases such as cancer, diabetes, Alzheimer’s, and heart disease.

“The integration of proteomic and genomic data analysis through a partnership with AB SCIEX and Illumina is an exciting collaboration that will bring democratization of computational efforts, general access and standardization of data analysis, and provide a platform for systems biology in life sciences,” said Leroy Hood, President of the Institute for System Biology in a press release.

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The patented AB SCIEX SWATH™ Proteomics software solves the “missing data problem” wherein traditional “shotgun” proteomics measures an incomplete set of proteins that are difficult to reproduce. SWATH™ makes reproducible proteome research feasible for the first time across many samples and is further enhanced through integration with Illumina NGS technologies.

“SWATH™ software is a patented innovation that allows thousands of proteins to be examined at once with almost no method development, and now with our cloud-based applications customers can process data 50 times faster,” said Rainer Blair, President of AB SCIEX in a press release. “The OneOmics project will enable better outcomes in omics research. We have developed four SWATH apps to support processing, analyzing, and visualization of proteomics mass spec data to extract biological insights.”

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The AB SCIEX SWATH™ Cloud Toolkit brings a growing list of BaseSpace apps to extract biological insight from SWATH™ proteomics mass spectrometry data, including:

  • Protein Expression Extractor – for processing raw mass spectrometry data
  • Protein Expression Assembler – for protein fold-change analysis
  • Protein Expression Browser – to visualize results in biological context
  • Protein Expression Analytics – for data quality review

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