"Mean Girls," Vince Gill Top Pittsburgh Weekend Events

PITTSBURGH, PA - “Mean Girls” revolves around Cady Heron adjusting to the vicious ways of her strange new home in suburban Illinois. The naïve newbie falls prey to a trio of lionized frenemies led by the charming but ruthless Regina George. But when Cady devises a plan to end Regina’s reign, she learns the hard way that you can’t cross a queen bee without getting stung.

Direct from Broadway, "Mean Girls" is the hit musical from an award-winning creative team, including book writer Tina Fey ("30 Rock"), composer Jeff Richmond ("Unbreakable Kimmy Schmidt"), lyricist Nell Benjamin ("Legally Blonde") and director Casey Nicholaw ("The Book of Mormon").

You can catch “Mean Girls” at the Benedum Center, Downtown, on Oct. 31 at 7:30 p.m.; Nov. 1 at 8 p.m.; Nov. 2 at 2 p.m. and 8 p.m. and Nov. 3 at 1 p.m. and 6:30 p.m.

Other weekend highlights:

• Chelsea Handler, Nov. 1, 8 p.m., Byham Theater, Downtown

Regarded as one of the most successful figures in entertainment today, Chelsea Handler and her talk shows, best-selling books, and stand-up comedy have attracted fans worldwide. After a successful seven-year run as the host of E!’s top-rated “Chelsea Lately,” Handler launched an all-new talk show, “Chelsea” for Netflix in May 2016. You can catch her at the Byham on Friday.

• Vince Gill, Nov. 1, 7:30 p.m., Heinz Hall

He’s been touring as one of the Eagles in recent years, but Gill leaves the rest of the birds behind for this solo show. one of the most celebrated country artists of all-time, Gill has sold more than r 24 million albums throughout his career and has won 20 Grammy Awards - more than any other male country artist in history.

• EQT Pittsburgh 10 Miler, Nov. 2 8 a.m. Station Square.

This one-of-a-kind race will take runners through 10 miles of Pittsburgh’s history, fandom, and quirkiest traditions. Each mile along the course will feature a different Pittsburgh tradition, icon, or staple, and among the 4,500 expected participants will be local video star Pittsburgh Dad and former Steeler Chris Hoke.

• Steelers vs. Indianapolis Colts, Nov. 3, 1 p.m. Heinz Field

The Steelers can climb to mediocrity and even their record at 4-4 with a victory against Indianapolis, something that seemed inconceivable when they started out 1-4. Will the power of the classic Styx song “Renegade” propel them to victory?