University Of Mississippi Medical Center: Factors Needed For Breast Cancer Metastasis Identified

Press release from the University of Mississippi Medical Center:

July 27, 2021

Dr. Marcus Zachariah, a member of the CCRI Interdisciplinary Brain and CNS care team and a researcher, is co-lead author of a landmark study on breast cancer brain metastasis, “HIF1A signaling selectively supports proliferation of breast cancer in the brain” recently published in the Nature Communications journal.

Zachariah, a neurosurgeon, and his colleagues identified changes in metabolism critical for growth of breast cancer cells in the brain during metastasis.

Notably, interfering with these metabolic alterations inhibited brain-specific cancer cell growth. This research sheds light on factors important for brain metastasis and opens the door to investigation of new drugs to target brain metastasis.

This press release was produced by the University of Mississippi Medical Center. The views expressed here are the author’s own.