Four dozen people were named in Thursday's indictment targeting a Harlem drug ring called "Main Event," based near Riverside Drive.
Kuldip Singh, 21, was a victim of the August shooting on 131st Street in which five people are still being sought by police.
A 61-year-old man died after being hit by a Jeep as he crossed Fifth Avenue toward Marcus Garvey Park, police said.
Police are looking for at least five people in connection with a shooting in Central Harlem that severely injured two people.
A fire at an East Harlem apartment building injured more than a dozen people and burned for more than two hours on Saturday.
An unrelated traffic accident reportedly helped police find the man accused of fatally shooting 15-year-old Amir James in East Harlem.
See the latest announcement from the Manhattan District Attorney's Office.
Two men say they were assaulted and seriously injured by police in East Harlem after being falsely accused of participating in a fight.
The 38-year-old victim was in the passenger seat of a parked car on 150th St. and 8th Ave. by a gunman who escaped after the shooting.
Thirteen alleged members of East Harlem's "Chico Gang" have been arrested after over a dozen shootings, including some that hit bystanders.
A man is accused of murdering a fellow East Harlem resident by punching him repeatedly and tossing him down a staircase, police said.
Police are looking for a man captured on video firing shots in the middle of Adam Clayton Powell, Jr. Boulevard on a recent afternoon.
A man was critically injured Tuesday when he was hit by a train at a Harlem station, the second such accident in two days.
A subway motorman watched a man leap in front of his train as it pulled into a Harlem subway station Monday, police said.
Police asked for help identifying a man accused of shooting someone in West Harlem before scooting away on a moped.
Police are seeking the public's help identifying two men in connection with a series of robberies in Upper Manhattan.
A 38-year-old woman was found fatally stabbed Wednesday in a stairwell at an East Harlem housing complex, police said.
One man was fatally shot and another stabbed to death during the May fight in Harlem. The stabber remains at large, police said.
A 19-year-old was fatally shot on a Harlem street corner Monday night, police said. No arrests have been made.
A 26-year-old woman was found dead at an East Harlem shelter early Sunday, police said. The cause remains unclear.
A man who may have been trying to cross the tracks was hit and killed by a train Monday morning at the 116th Street Station.
Police are trying to figure out why a group of people attacked and robbed a 61-year-old woman using a walker on a Harlem sidewalk this week.
An NYPD sergeant accused of punching a handcuffed man at a Harlem subway station has been suspended and charged with assault.
Five members of Tekashi 6ix9ine's security team, including an ex-NYPD detective, are charged with chasing a man across Harlem last summer.
A man racing off the Harlem River Drive died Monday when his car flipped on the exit ramp in East Harlem, ejecting him from the vehicle.
Police tried to explain why a Black man accused of holding open an exit door ended up being tased in a Harlem subway station last week.
New photos show a person of interest in the June shooting in Central Harlem that left a 31-year-old man dead.
A Long Island man is accused of using false documents and shell companies to steal two Harlem brownstones — one of which he still owns.
Police are searching for two men seen on video firing shots from a Lime electric scooter in East Harlem.
A 32-year-old man was ambushed and shot in broad daylight Monday across from a Harlem public housing complex, police said.