- Acetaminophen is the number one cause of acute liver failure in the US. Taking just a little more than the recommended dose over the course of several days or weeks (“staggered overdosing”) is far more risky than taking one large overdose
- Recent research suggests that acetaminophen also significantly increases your risk of kidney dysfunction if taken with alcohol—even if the amount of alcohol is small
- Previous research suggests acetaminophen might render vaccinations less effective when administered together
