The two fatalities were reported early Sunday morning on the 5 Freeway in Irvine, the California Highway Patrol reported.
The man defrauded victims who paid more than $3 million for COVID-related medical protective equipment that was never delivered.
A suspected package theft suspect was arrested in south Orange County this week, the Irvine Police Department reported.
Authorities found more than 50 cats at a South Orange County residence where a woman was reportedly breeding and selling them.
A man was found at the bottom of an embankment in Irvine after he had fallen off of his bike, authorities said.
Two people were found dead Thursday at a south Orange County hotel from a murder-suicide, authorities said.
A fire damaged a home in south Orange County Wednesday, with the Red Cross assisting the four residents in finding alternative housing.
The former General Motors manager took the bribes from a South Korean parts supplier in exchange for a major contract with the automaker.
A 37-year-old man suspected of stabbing his mother to death in Irvine was fatally shot by police responding to the attack Thursday.
Two people died when police responded to reports of a man attacking a woman Thursday afternoon, authorities say.
A man who was paralyzed and relied on a wheelchair was stabbed to death by a former caregiver in Irvine, police said.
A man ran his minivan into a home in Irvine where a dead person was found inside, but police don't believe it was the crash that killed him
Authorities are searching for a group of vandals on e-bikes responsible for a variety of damage at the Great Park in Irvine.
A teenage girl who was strangled then dumped in Irvine and set on fire nearly 15 years ago has been identified, police said Thursday.
The Orange County Fire Authority is praising a family in Lake Forest helping to keep a garage fire from spreading.
The fire department credits quick thinking by the homeowners for limiting the damage.
A man indicted in a fentanyl overdose death two years ago was arrested Tuesday and is scheduled to be arraigned in federal court.
An Indiana man was charged Tuesday with killing an 18-year-old in a sober-living facility in south Orange County.
A 24-year-old man was arrested Monday on suspicion of killing an 18-year-old man at a sober-living facility in Irvine.
Jurors in Orange County have reached a verdict in the trial of Samuel Woodward, who is accused of stabbing his gay classmate in 2018.
While the defense pleaded for leniency, the prosecution said to reject first-degree murder, "You have to believe a liar."
Samuel Woodward engaged in (neo-Nazi) ideas for at least 3 months in Texas, she said on the stand. "For a time, he believed those things."
The condition affects up to 1 percent of the population and in most cases is not dangerous, according to the Cleveland Clinic.
Six years after the brutal slaying and purported hate crime of Blaze Bernstein in a Lake Forest park, Sam Woodward faced cross-examination.
The man charged with the alleged hate-crime fatal stabbing of a former gay classmate in Foothill Ranch took to the stand Thursday.
Two teenage girls, including one from Orange County, were killed after their jet ski crashed into a boat on a lake in northeast Illinois.
Support for Pinoy Pam's Best, a beloved Filipino restaurant and "mom and pop" store, is growing in Lake Forest after months of vandalism.
The man charged with killing the 19-year-old Blaze Bernstein because he was gay took the stand Thursday in his own defense.
Two people were injured in the crash that was reported at the intersection of Jeronimo Road and Heidi Avenue.
The 22-year-old Irvine man was sentenced Thursday to six years in federal prison for his part in the firebombing attack in Costa Mesa.
The group of more than two dozen students rallied outside UC Irvine Chancellor Howard Gilman's house in University Hills on Memorial Day.
The new site is the latest step in Goodwill's plan to double its impact across Orange County over the next 10 years.
The driver was fatally shot Thursday in Irvine, and a possible suspect was arrested hours later after a brief standoff with SWAT officers.
UC Irvine students were told classes will meet remotely Thursday following what Chancellor Howard called "a sad day for our university."
A protest regarding the war in Palestine at UC Irvine turned violent Wednesday, prompting calls for police and a warning to students.
An Irvine man died after losing control of his car and crashing into a tree and pole, and police are looking for a possible suspect.
The physician was charged with sexually assaulting two of his patients when he grabbed their breasts during medical exams.
Authorities issued an advisory for residents to avoid the area at 1:40 p.m. Tuesday.
A quick-thinking officer with the Irvine Police Department helped a woman in need this week.
The dog was rescued from a fourth-floor balcony at an Irvine residence after being locked out while no one was home.